Detection of DNA translocation using single wall carbon nanotube electrodes on Si₃N₄ nanopore
Keng-yu Yeh1,2,3*, Shiu-yuan Chang4, Kuei-Shu Chang liao3, Chii-dong Chen1
1Institute of Physics, Academia Sinica, Taipei, Taiwan
2Taiwan International Graduate Program, Academia Sinica, Taipei, Taiwan
3Engineering and System Science, National Tsing Hua University, Hsinchu, Taiwan
4Department of Physics, National Chang Hua University of Education, Chang Hua, Taiwan
* presenting author:耕余葉,
Single-walled carbon nanotubes(SWCNTs) is well known with its nanometer scaled conformation, good conductivity and material stability. These advantages lead SWCNTs a nature material for single DNA detection technology as a nanoelectrode for improving the technology of DNA detection by Si₃N₄ nanopore . We successfully fabricated the device with 10 nm in diameter of Si₃N₄ nanopore and SWCNTs nearly 1 nm diameter prepared by lithography and TEM drilling process. Simultaneous signal acquire in both ionic blockade current signal and the increase of transverse current signal during the single strand DNA translocation is also observed in our experiment. We examine the high correlation between these two signals as a real-time control of the SWCNT-based sensing device.

Keywords: DNA translocation, Silicon Nitride nanopore, Single wall carbon nanotube